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July 12, 2021
 min read

What is the best way to use CBD oil for restless legs?

cbd oil for restless legs
 Anthony Clement
Written by  
Anthony Clement
July 12, 2021

table of Contents

Restless legs syndrome is a troublesome movement disorder that causes uncontrollable movement of the legs. What's even worse, severe RLS patient will experience a lot of pain during this period. Experts speculate that CBD tinctures might be able to help with both the underlying neurological disorder as well as the chronic pain that comes with this unpleasant sensation.

It is also believed that the substance may help patients who are suffering from Parkinson's disease. Keep in mind that it shouldn't replace the traditional medication, though. What's interesting is that the only hemp derived drug is Epidiolex, which is used for certain types of muscle spasms. So, it isn't hard to believe that medical hemp oil might provide relief for other muscle related issues.

Anyway, here is how CBD oil for restless legs might work and how to properly use the substance.

What do you need to know about CBD and RLS?

RLS symptoms are easy to notice. An RLS sufferer will have uncontrollable movement of the legs, which is usually followed by itching and aching. During the night, a person will also experience twitching in the legs, gradually turning to a sleep disorder.

There are several ways cannabidiol might help for restless leg syndrome symptoms. The substance is often advertised as a pain relief product. Among others, it is meant to reduce stress, relax muscles, and bring about longer uninterrupted sleep.

Besides addressing issues directly, medicinal cannabis might work by improving the protective function. In other words, it might protect nerve cells from further damage, thus stopping the degenerative process.

What causes restless legs syndrome?

The condition is also known as Willis Ekbom disease. It causes an uncontrollable need to move your legs. This is followed by an uncomfortable sensation. As mentioned, it is especially common during the night, which is why the majority of LRS patients have very bad sleeping patterns.

Like many other neurological disorders, we don't know everything about RLS. It is presumed that the issue is caused by iron deficiency in the brain. To be precise, a person will experience an imbalance between iron levels in the brain and the rest of the body.

The major risk group are women with fibromyalgia. These two can have a negative impact on each other so, if you're suffering from a sleep disorder caused by RLS, this might worsen your fibromyalgia symptom. As a result, RLS sufferers will experience chronic fatigue, stiffness, joint, and muscle pain.

The condition is usually treated by using dopamine agonists. These drugs should increase your dopamine levels, thus improving your ability to control bodily movements. Unfortunately, prolonged use of the medication can be counterproductive and even cause severe LRS.

Besides dopamine drugs, a patient might also use Alpha-2-delta ligands (reduce seizures), benzodiazepines (meant to address anxiety and sleep disorders), as well as opioids for pain. All in all, a person might be forced to take a combination of different drugs during the therapy. Some of them might go against each other, potentially worsening the symptoms or causing additional side effects.

This is precisely why people are considering alternatives such as CBD topicals, CBD cream, and other CBD product.

How can CBD affect RLS symptoms?

Medical marijuana and medical hemp have a lot of different properties, some of which might come in handy when dealing with restless legs syndrome. For the purpose of this article, we will focus on medical hemp CBD products that are usually legal, unlike medical hemp.

RLS symptoms are most noticeable during the night. In fact, restless legs disorder is one of the most common sleep conditions in the world that affects about 10% of the global population.

As mentioned, cannabidiol shows a lot of promise when addressing sleep issues. The substance works two fold: it has sedative properties meant to relax your brain while also reducing stress levels, and it might also work by reducing muscle spasms. Based on overwhelming data, the substance is especially potent for this particular problem.

Experts believe that medical hemp works by stimulating cannabinoid receptors in the human body. These receptors are a part of a larger endocannabinoid system that should provide homeostasis to the body. It might have an impact on various internal functions such as sleep, mood, appetite, protection, regeneration, reproduction, etc.

Among others, it is believed that the substance might provide major relief and have some impact on inflammation.

What are the main advantages and disadvantages of CBD oil for restless legs syndrome?


  • CBD is regarded as a safe substance by the World Health Organization. It is also allowed for athletic use by the World Anti-Doping Agency.
  • The substance might address various RLS issues. Even if it doesn't, there shouldn't be any major drawbacks when using the product.
  • In a lot of countries, these products are easily attainable, and oftentimes, you won't even need a prescription.


  • We simply don't know enough about the substance. Most of these claims are within the realm of theory.
  • There is still a chance to experience some minor drawbacks, which can have a really bad impact on a person who is already struggling with RLS symptoms.
  • The hemp market is not properly regulated, which is why the quality of substances may vary significantly. So, the potential benefits might vary significantly based on what you're administering

How does cannabidiol compare to other treatments?

A lot of people are willing to try CBD because of the volatile side effects caused by traditional drugs. They will also experiment with some other supplements and wellness products.

For example, a lot of RLS patients will use iron supplements as the first response to restless legs syndrome. Unfortunately, these products may cause nausea, constipation, and stomach pain. It seems that the intravenous version of the supplement is much better and less likely to cause drawbacks.

Magnesium is another popular item that people often use. It might help relax muscles and, in particular, provide relief for cramps. This mineral works as a muscle relaxant, and it shouldn't cause any major side effects.

Doctors also recommend increased physical activity. Stretching the legs is one of the first things you should try. Besides that, you should start exercising and especially walking and running. This might help relieve some of that pain.

How do you administer CBD oil for restless legs syndrome?

CBD products come in various shapes and forms. You can experiment with lots of different products but, if we're talking about CBD oil, it is a substance that is used topically or sublingually.

During sublingual administration, a person will put the substance under the tongue. You need to swirl it around for several minutes so that the sublingual gland can absorb the chemical. Sublingual administration provides a wholesome impact on the body, and it is the optimal application if you wish to improve sleep patterns.

The second method is topical administration. You can use it to put cannabidiol on a specific muscle area that feels sore. The substance should penetrate the surface tissue and bring relief to the muscles. Make sure to use the product in moderation.

When administering Cannabis oil, we recommend that you start with a smaller dose and increase it as you go. While the product is very safe, an increased quantity may cause side effects or worsen them. For example, you might feel extreme drowsiness or get diarrhea when you take too much sublingual cannabidiol.

Maroon, J., & Bost, J. (2018). Review of the neurological benefits of phytocannabinoids. Surgical neurology international


Connor, J., Ponnuru, P., Wang, X., S., Patton, S., Allen, R., Earley, C., (2011), Profile of altered brain iron acquisition in restless legs syndrome. Brain: a journal of neurology