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July 12, 2021
 min read

Is CBD oil for lyme disease a legit treatment and how does it affect symptoms?

cbd oil lyme disease
 Anthony Clement
Written by  
Anthony Clement
July 12, 2021

table of Contents

While most Lyme disease patients will start antibiotic treatment, these drugs can have a strong impact on your immune system, often leading to side effects.

A lot of experts believe that CBD topicals can provide mild pain relief. The substance might help with inflammation, but also some other issues when you administer it sublingually. For example, it might address common Lyme symptoms such as chronic fatigue syndrome.

Lyme disease sufferers may experience numerous issues. Medical hemp oil and other cannabis topicals have a wholesome impact on the human body and might relieve some of these problems. Basically, CBD and other cannabinoids might affect the endocannabinoid system, thus providing various wellness benefits.

Anyway, in this article, we will explore CBD oil for Lyme disease and how it might potentially work.

What is Lyme disease?

This is a tick borne disease that is becoming more common in the western world. An infected tick may carry a bacterium Borrelia Burgdorferi. Upon tick bite, Borrelia bacterium is passed on to a human host, thus causing Lyme disease.

You can get this condition whenever you walk in nature or do some other outdoor activity. As you well know, ticks can easily be found in the grass, and it is really hard to prevent their bite, especially during summertime.

The good news is that Lyme disease sufferers cannot transfer this condition to others. The biggest problem with this condition is that its symptoms will worsen if you don’t treat it in time. Among others, untreated Lyme disease can lead to chronic issues like chronic fatigue syndrome and chronic pain.

Ideally, Lyme patients should react as soon as they notice that something's wrong. Keep in mind that before you can start antibiotic treatment, you need to perform the necessary lab analysis and properly diagnose the condition. For example, Epstein Barr virus (or EBV) can cause false positives during Lyme disease testing, so that's something you should be aware of.

How to recognize symptoms of Lyme disease?

This ailment will cause all sorts of issues. It is very important to recognize them as soon as possible. That way, you can prevent chronic Lyme disease and other potential chronic conditions that come with it.

Of course, most people will notice a tick bite from the get go. One of the earliest signs of Lyme disease is erythema migrans. This is an expanding rash that will affect the bite spot.

Unfortunately, even if you manage to treat the condition with antibiotics, you might experience PTLD or post treatment Lyme disease syndrome. This issue is characterized by joint pain and other symptoms.

Mild symptoms of Lyme disease

  • Irritation around the bite spot
  • Swollen lymph nodes
  • Loss of mobility
  • Overall pain
  • Headache
  • Inflammation

Severe symptoms of Lyme disease

  • Arthritis
  • Peripheral neuropathy
  • Facial paralysis
  • Severe joint pain
  • Depression
  • Anxiety
  • Confusion

Keep in mind that some of these issues might become permanent. As already mentioned, you might also have to deal with post treatment problems. Lyme disease patients may develop physiological problems and nerve issues. In extreme cases, a patient might become suicidal.

Does CBD oil work for Lyme disease?

CBD oil and cannabis oil might provide some relief for the symptoms, but they shouldn’t be used as a treatment for the underlying condition. Instead, your doctor should recommend antibiotics as soon as possible.

If you were to use CBD oil, you might be able to use it for some of the symptoms, such as chronic pain or inflammation. This is especially true if a person has suffered permanent neurological damage and has to deal with pain on a constant basis.

Pure CBD oil might affect CB1 receptors that are a part of the endocannabinoid system. By doing so, the substance might harmonize various internal processes such as sleep, mood, pain, stress, regeneration, etc. That way, it might help with numerous issues caused by this infectious disease.

Experts believe that the product might also carry certain antimicrobial properties. Nevertheless, you shouldn’t try to replace antibiotic therapy, as CBD oil cannot substitute the traditional drugs.

CBD oil Lyme disease: Clinical data

Nowadays, scientists perform various studies involving CBD oil as we still have a lot of questions regarding the substance’s potential effects and internal mechanisms.

Although researchers haven’t directly explored CBD oil as a potential treatment for Lyme disease, they have done various other related studies. For example, experts have done several tests meant to examine cannabidiol’s effect on pain and inflammation.

One of the more notable studies was done back in 2013. During this clinical trial, the test subjects were given CBD oil as a way of addressing cancer related pain. As you well know, pain associated with cancer is usually the strongest type of chronic pain. In most cases, even the strong, traditional painkillers cannot provide the necessary relief.

After administering the substance, the test subjects have shown improved pain, insomnia, and fatigue scores. Furthermore, scientists haven’t noticed any long term issues after administering the chemical. The lyme patients have shown great tolerance towards the product, and it was very efficient for the majority of them.

During another study, researchers explored the potential impact of CBD oil on migraines and headaches. These are also common symptoms of Lyme disease and something that medical hemp oil can potentially address. Again, the substance has shown great results.

Although experts wanted to focus on headaches and migraines, they’ve also noticed that the product might help with muscle spasms. Again, this is another issue that comes with the condition. Test subjects have experienced great improvements without suffering from any long term problems.

According to this limited data, it seems that cannabidiol might work in several different ways for Lyme disease symptoms. Then again, these were very limited tests, and we don’t have any conclusive data that the product would actually work in a real world situation.

Furthermore, people might experience different effects based on the substance they're using. Unfortunately, the global CBD market is not well regulated so you can find all sorts of products out there. Some of them are advertised as medical hemp products rich in CBD, and they might have a low concentration of the substance or no CBD whatsoever.

How to use CBD oil for Lyme disease symptoms?

CBD oil can be used in two different ways: sublingually and topically.

When you wish to use cannabidiol oil sublingually, you need to put it under your tongue. Swirl it around for a couple of minutes so that the sublingual gland can absorb it. That way, the majority of the substance will reach your bloodstream within 10 to 15 minutes.

The main benefit of sublingual administration is that the chemical can reach your bloodstream and provide benefits in a relatively short amount of time. This can be very important for patients who are suffering from unbearable pain or spasms.

Keep in mind that sublingual administration will affect your whole body, thus providing general wellness benefits. It won’t target a specific area, but instead, it should have a complete impact.

Topical administration is the second approach. This method is much better if you wish to address skin or muscle tissue problems.

Unfortunately, topical administration can cause issues if you place the substance on a wounded or infected area. While it might provide some benefits for swelling, pain, and inflammation, we are not certain how our bodies would react if you put it directly on the bitten area.

Because of that, it is much better if you go with a sublingual application.

What is the optimal CBD dose?  

Finding the right CBD oil dosage can be tricky. There are numerous factors that you need to consider, such as the patient's weight, CBD tolerance, the severity of symptoms, age, sex, strength for a product, etc.

In general, most people will take about 20 to 30mg per day. If the symptoms are really strong, you might consider administering the product several times a day or even in a higher dosage.

Keep in mind that CBD oil might lead to some side effects such as:

  • Dry mouth
  • Dizziness
  • Diarrhea
  • Change in blood pressure and appetite
  • Drowsiness

These potential side effects tend to worsen if you overdo it with dosage. Because of that, it is much better to start with a smaller quantity and increase it as you go. Most of these side effects will stop as soon as you stop using the product. However, if they do persist, make sure to contact a medical professional and ask for assistance.

Will I get high from CBD oil?

As previously mentioned, CBD products are generally regarded as safe substances. Even if you use them for a prolonged period of time, they are unlikely to cause any side effects.

One of the potential problems comes in the form of high THC concentration. While hemp extracted CBD oil shouldn’t cause any issues, it is a completely different story if a substance is extracted from marijuana. This plant has high THC content with low CBD quantity. While both of these chemicals have wellness potential, higher quantities of THC will cause psychoactive problems.

If you use marijuana extracts for a longer period of time, in larger quantities, you might experience mental issues. Experts claim that long term use of the substance probably leads to loss of IQ. In some extreme cases, patients have even experienced psychosis.

Anyway, as long as a product is extracted from hemp, and if it has appropriate THC levels (below 0.3%), it shouldn't get you high. Our bodies can easily metabolize a smaller quantity of the substance. On top of that, a patient shouldn't be able to have psychedelic episodes.

Fine, P., Rosenfeld, M., (2013), The Endocannabinoid System, Cannabinoids, and Pain, Rambam Maimonides Medical Journal


Pavletic, A., Marques, A., (2017), Early Disseminated Lyme Disease Causing False-Positive Serology for Primary Epstein-Barr Virus Infection: Report of 2 Cases, Clinical Infectious Diseases, Volume 65, Issue 2, Oxford, United Kingdom


Johnson, J.R., Lossignol, D., Burnell-Nugent, M., Fallon, MT., (2013), An open-label extension study to investigate the long-term safety and tolerability of THC/CBD oromucosal spray and oromucosal THC spray in patients with terminal cancer-related pain refractory to strong opioid analgesics, PubMed J Pain Symptom Manage